Question

A 26-year-old pregnant woman at 34 weeks with known rheumatic mitral valve disease and previous rheumatic fever asks about her prophylaxis injections. She has been receiving benzathine benzylpenicillin 1.2 million units IM every 4 weeks. What is the most appropriate advice?

Accepted Answer

Continue regular benzathine benzylpenicillin injections throughout pregnancy

Answer

Stop prophylaxis in pregnancy due to risk of teratogenicity

Answer

Reduce the dose to 600 000 units IM every 8 weeks

Answer

Switch to oral amoxicillin for the remainder of pregnancy

Answer

Delay prophylaxis until 6 weeks postpartum

Practice question

A 26-year-old pregnant woman at 34 weeks with known rheumatic mitral valve disease and previous rheumatic fever asks about her prophylaxis injections. She has been receiving benzathine benzylpenicillin 1.2 million units IM every 4 weeks. What is the most appropriate advice?