Question

A 65-year-old man with a 40 pack-year smoking history presents with a chronic cough and sputum production. Spirometry shows FEV₁/FVC ratio of 0.55 and FEV₁ 60% predicted, with minimal reversibility. According to COPD-X, which intervention provides the greatest mortality benefit?

Accepted Answer

Long-term oxygen therapy in those with chronic severe hypoxaemia

Answer

Regular short-acting beta₂ agonist use

Answer

Long-acting bronchodilator therapy alone

Answer

Mucolytic therapy

Answer

Inhaled corticosteroid monotherapy

Practice question

A 65-year-old man with a 40 pack-year smoking history presents with a chronic cough and sputum production. Spirometry shows FEV₁/FVC ratio of 0.55 and FEV₁ 60% predicted, with minimal reversibility. According to COPD-X, which intervention provides the greatest mortality benefit?