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MediumRespiratoryAcute COPD exacerbation with hypercapnic failureca-mccqe1ca-rcpsc-em

A 72-year-old man with COPD (FEV1 35% predicted) presents with increased dyspnoea, sputum volume, and purulence. On arrival, RR is 30 breaths/min, SpO2 84% on room air, pH 7.28, PaCO2 8.0 kPa (60 mmHg), PaO2 56 mmHg on 4 L/min nasal prongs. Which intervention is most appropriate in addition to bronchodilators, steroids, and antibiotics?

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