MediumCardiologyHeart failure with reduced ejection fractionca-mccqe1ca-rcpsc-im
A 70-year-old woman with long-standing hypertension and prior anterior myocardial infarction presents with exertional dyspnoea and ankle swelling. Echocardiography shows a left ventricular ejection fraction of 30%. She is already on a maximally tolerated ACE inhibitor and a beta blocker. According to contemporary heart failure guidelines, which additional medication class has the strongest evidence for mortality reduction and should be added next?