Question

A 30-year-old pregnant woman at 16 weeks' gestation presents with dysuria and frequency. She is afebrile and otherwise well. Urinalysis shows nitrites and leucocytes. Urine culture is pending. What is the most appropriate empirical antibiotic therapy?

Accepted Answer

Nitrofurantoin 100 mg orally twice daily for 5 days (avoid near term)

Answer

Trimethoprim 300 mg orally at night for 3 days

Answer

Ciprofloxacin 500 mg orally twice daily for 7 days

Answer

No antibiotics are required in pregnancy for asymptomatic bacteriuria

Answer

Single dose fosfomycin 3 g is contraindicated in pregnancy

Practice question

A 30-year-old pregnant woman at 16 weeks' gestation presents with dysuria and frequency. She is afebrile and otherwise well. Urinalysis shows nitrites and leucocytes. Urine culture is pending. What is the most appropriate empirical antibiotic therapy?