Question

A 59-year-old woman without known cardiovascular disease has a 10-year atherosclerotic cardiovascular disease risk of 14% using a validated Canadian risk calculator. Her LDL-C is 3.6 mmol/L, HDL-C 1.1 mmol/L and triglycerides 1.8 mmol/L. According to the 2021 Canadian Cardiovascular Society dyslipidaemia guideline, what is the most appropriate lipid-lowering strategy?

Accepted Answer

Start a high-intensity statin aiming for LDL-C <1.8 mmol/L or >=50% reduction

Answer

No statin therapy; repeat lipid profile in 5 years

Answer

Start a moderate-intensity statin aiming for LDL-C <2.5 mmol/L

Answer

Lifestyle modification only; statins reserved for secondary prevention

Answer

Start ezetimibe monotherapy

Practice question