Question

A 45-year-old woman with chronic hepatitis B is found to have HBsAg positive, HBeAg negative, HBV DNA 1,000 IU/mL and normal ALT on repeated testing. Ultrasound shows no cirrhosis. What is the most appropriate management strategy?

Accepted Answer

Observation with regular monitoring of ALT, HBV DNA and ultrasound for HCC surveillance

Answer

Immediate antiviral therapy for all chronic hepatitis B

Answer

Liver transplantation referral

Answer

High-dose corticosteroids

Answer

No follow-up required as ALT is normal

Practice question

A 45-year-old woman with chronic hepatitis B is found to have HBsAg positive, HBeAg negative, HBV DNA 1,000 IU/mL and normal ALT on repeated testing. Ultrasound shows no cirrhosis. What is the most appropriate management strategy?