Question

A 64-year-old woman with long-standing hypertension and type 2 diabetes has persistent albuminuria. Her eGFR is 48 mL/min/1.73 m². Which intervention is most important to slow progression of her diabetic kidney disease, in addition to glycaemic and blood pressure control?

Accepted Answer

Start an ACE inhibitor or ARB and titrate to maximal tolerated dose

Answer

Replace ACE inhibitor with a beta-blocker

Answer

Avoid renin-angiotensin system blockers to protect renal function

Answer

Aim for a systolic blood pressure consistently above 150 mm Hg

Answer

Use NSAIDs regularly for osteoarthritis pain

Practice question

A 64-year-old woman with long-standing hypertension and type 2 diabetes has persistent albuminuria. Her eGFR is 48 mL/min/1.73 m². Which intervention is most important to slow progression of her diabetic kidney disease, in addition to glycaemic and blood pressure control?