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HardCardiologyHeart failure with reduced ejection fractionau-amcau-racp

A 63-year-old woman presents with exertional dyspnoea and ankle swelling. Echocardiography reveals a left ventricular ejection fraction of 30% with global hypokinesis. She has controlled hypertension and type 2 diabetes. According to contemporary heart failure management principles in Australia, which pharmacological combination is the most appropriate foundational therapy (assuming no contraindications)?

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