Question

A 32-year-old woman presents with iron deficiency anaemia and chronic diarrhoea. Coeliac serology shows elevated tissue transglutaminase IgA and endomysial antibodies. Total IgA is normal. What is the most appropriate next diagnostic step?

Accepted Answer

Duodenal biopsy via upper endoscopy

Answer

HLA typing for DQ2/DQ8 only

Answer

Start a gluten-free diet without further investigation

Answer

Colonoscopy only

Answer

Capsule endoscopy

Practice question

A 32-year-old woman presents with iron deficiency anaemia and chronic diarrhoea. Coeliac serology shows elevated tissue transglutaminase IgA and endomysial antibodies. Total IgA is normal. What is the most appropriate next diagnostic step?