HardCardiologyHypertension with chronic kidney diseaseau-racpau-amc
A 64-year-old man with long-standing type 2 diabetes and hypertension has an eGFR of 42 mL/min/1.73 m² and an albumin:creatinine ratio of 45 mg/mmol on two occasions. Blood pressure is 148/88 mmHg on maximised amlodipine. Which is the most appropriate next step to optimise his blood pressure and renal protection?