Question

A 70-year-old man presents with severe back pain, anaemia, hypercalcaemia and renal impairment. Serum protein electrophoresis shows an M-protein and bone marrow biopsy reveals clonal plasma cells. What is the most likely diagnosis?

Accepted Answer

Multiple myeloma

Answer

Osteoporosis

Answer

Metastatic prostate cancer

Answer

Paget disease of bone

Answer

Primary hyperparathyroidism alone

Practice question

A 70-year-old man presents with severe back pain, anaemia, hypercalcaemia and renal impairment. Serum protein electrophoresis shows an M-protein and bone marrow biopsy reveals clonal plasma cells. What is the most likely diagnosis?