Question

A 35-year-old man in the emergency department has been having continuous generalised tonic-clonic seizures for 10 minutes without regaining consciousness. IV access is available. What is the most appropriate first-line pharmacological treatment?

Accepted Answer

Intravenous midazolam or diazepam bolus

Answer

Intravenous phenytoin loading dose

Answer

Oral diazepam

Answer

Intravenous sodium valproate as first-line

Answer

No drug treatment until 30 minutes have elapsed

Practice question

A 35-year-old man in the emergency department has been having continuous generalised tonic-clonic seizures for 10 minutes without regaining consciousness. IV access is available. What is the most appropriate first-line pharmacological treatment?