Question

A 40-year-old man immigrated from an HBV-endemic country 10 years ago. His serology today shows HBsAg negative, anti-HBs positive, anti-HBc positive. He has normal liver enzymes. What is the most appropriate interpretation and management?

Accepted Answer

Resolved past infection with immunity; no vaccination required

Answer

Susceptible; offer full hepatitis B vaccination series

Answer

Acute hepatitis B infection; start antiviral therapy

Answer

Chronic hepatitis B infection; refer urgently for antiviral therapy

Answer

False-positive serology; repeat tests in 1 year

Practice question

A 40-year-old man immigrated from an HBV-endemic country 10 years ago. His serology today shows HBsAg negative, anti-HBs positive, anti-HBc positive. He has normal liver enzymes. What is the most appropriate interpretation and management?