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MediumPsychiatryMajor depressive disorderca-mccqe1ca-ccfpca-rcpsc-im

A 28 year old woman presents with low mood, anhedonia, poor concentration and early morning awakening for the past 6 weeks. She has passive thoughts that life is not worth living but no active plan. There is no history of mania, psychosis or substance misuse. According to CANMAT 2023 guidelines, what is the most appropriate first line treatment approach?

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