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HardCardiologyST-elevation myocardial infarction in rural settingau-amcau-acem

A 58‑year‑old man presents to a small rural hospital 3 hours after onset of severe central chest pain. ECG shows 3 mm ST elevation in leads II, III and aVF. There is no access to on‑site PCI; the nearest PCI centre is 4 hours away by road and weather prevents aeromedical transfer. What is the most appropriate reperfusion strategy?

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