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MediumHepatologyPrimary biliary cholangitisau-amcau-racp

A 41-year-old woman presents with fatigue, pruritus and right upper quadrant discomfort. LFTs show ALP 420 U/L (normal <110), GGT 350 U/L, ALT 60 U/L, AST 55 U/L. Ultrasound shows normal bile ducts and no gallstones. Antimitochondrial antibody is strongly positive. What is the most likely diagnosis?

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