HardRespiratoryAcute hypercapnic respiratory failure in COPDau-amcau-acemau-racp
A 62-year-old man with COPD presents to the ED with worsening dyspnoea and productive cough for 5 days. ABG on room air shows pH 7.30, PaCO2 60 mmHg, PaO2 50 mmHg, HCO3- 26 mmol/L. He is drowsy with use of accessory muscles. What is the most appropriate immediate ventilatory support?