A 73-year-old woman with bilateral knee pain due to osteoarthritis has difficulty walking more than one block. Radiographs show moderate joint space narrowing. She prefers to avoid surgery. What is the most appropriate initial management strategy?ALong-term high-dose NSAIDs without non-pharmacological measuresBIntra-articular corticosteroid injections as sole therapyCNon-pharmacological therapy including exercise, weight loss and physiotherapy, plus intermittent simple analgesicsDImmediate total knee arthroplastyELong-term systemic opioids for pain controlCheck my answer