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MediumCardiologyST-elevation myocardial infarctionau-amcau-acem

A 67-year-old man presents to a small rural emergency department 45 minutes after the onset of severe central chest pain radiating to his left arm, associated with diaphoresis and nausea. ECG shows 3 mm ST elevation in leads V2-V4. The nearest PCI-capable centre is 3 hours away by road and 90 minutes by retrieval service. What is the most appropriate immediate reperfusion strategy?

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