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MediumCardiologyST-elevation myocardial infarctionca-mccqe1ca-rcpsc-emca-rcpsc-im

A 68-year-old man presents to a rural emergency department with 90 minutes of crushing central chest pain and diaphoresis. ECG shows ST elevation in leads II, III and aVF. The nearest PCI-capable centre is 4 hours away by ground and 3 hours by air; air transport is grounded by severe weather. What is the most appropriate reperfusion strategy?

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