Question

A 55-year-old man presents with acute monoarthritis of the first metatarsophalangeal joint. The joint is swollen, red and extremely tender. Serum uric acid is mildly elevated. What is the most appropriate initial pharmacologic treatment for this attack?

Accepted Answer

Colchicine or NSAID for acute flare

Answer

Low-dose allopurinol

Answer

Probenecid

Answer

Intra-articular corticosteroid injection only after urate-lowering therapy

Answer

Oral prednisone 5 mg daily for 6 months

Practice question

A 55-year-old man presents with acute monoarthritis of the first metatarsophalangeal joint. The joint is swollen, red and extremely tender. Serum uric acid is mildly elevated. What is the most appropriate initial pharmacologic treatment for this attack?