Question

A 26-year-old man presents 36 hours after a high-risk condomless receptive anal sexual exposure to a partner of unknown HIV status. He has normal renal function, is not on PrEP, and has no symptoms. According to Canadian HIV PEP guidance, what is the most appropriate management?

Accepted Answer

Start triple-drug HIV post-exposure prophylaxis for 28 days

Answer

Reassure; PEP is not indicated after 24 hours

Answer

Give a single dose of antiretroviral therapy

Answer

Wait for the source partner to be tested before starting any treatment

Answer

Start dual therapy with lamivudine and zidovudine only

Practice question

A 26-year-old man presents 36 hours after a high-risk condomless receptive anal sexual exposure to a partner of unknown HIV status. He has normal renal function, is not on PrEP, and has no symptoms. According to Canadian HIV PEP guidance, what is the most appropriate management?