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HardRural & Remote MedicineST-elevation myocardial infarction management in rural settingsau-amcau-acem

A 59-year-old woman presents to the emergency department of a small rural hospital 3 hours after onset of severe central chest pain. ECG shows 3 mm ST elevation in leads II, III and aVF. The nearest PCI-capable centre is 3 hours away by road, and helicopter transfer is unavailable due to weather. What is the most appropriate reperfusion strategy?

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