Question

A 68 year old man presents with bone pain, fatigue and recurrent infections. Blood tests show normocytic anaemia, hypercalcaemia and creatinine 180 µmol/L. Serum protein electrophoresis reveals an M spike and bone marrow biopsy shows 40% clonal plasma cells. What is the most likely diagnosis?

Accepted Answer

Multiple myeloma

Answer

Chronic lymphocytic leukaemia

Answer

Monoclonal gammopathy of undetermined significance (MGUS)

Answer

Osteoporosis

Answer

Waldenström macroglobulinaemia

Practice question

A 68 year old man presents with bone pain, fatigue and recurrent infections. Blood tests show normocytic anaemia, hypercalcaemia and creatinine 180 µmol/L. Serum protein electrophoresis reveals an M spike and bone marrow biopsy shows 40% clonal plasma cells. What is the most likely diagnosis?