Question

A 56-year-old obese man with long-standing heartburn has been on PPI therapy for several years. He now reports new-onset dysphagia and unintentional weight loss of 6 kg over 3 months. What is the most appropriate next step?

Accepted Answer

Arrange urgent upper gastrointestinal endoscopy

Answer

Increase PPI dose and review in 3 months

Answer

Switch to an H2-receptor antagonist

Answer

Test and treat for Helicobacter pylori without further investigations

Answer

Advise lifestyle modification only

Practice question

A 56-year-old obese man with long-standing heartburn has been on PPI therapy for several years. He now reports new-onset dysphagia and unintentional weight loss of 6 kg over 3 months. What is the most appropriate next step?