A 32-year-old woman with known ulcerative colitis has a flare with bloody diarrhoea 6 times per day and mild abdominal pain. She has no systemic toxicity. What is the most appropriate initial pharmacological management?AHigh-dose oral mesalazine aloneBShort course of loperamideCSystemic corticosteroids (e.g. prednisolone) in addition to optimised 5-ASA therapyDStart thiopurine monotherapy immediatelyEBegin biologic therapy without prior steroidsCheck my answer