Question

A 35-year-old man presents to the emergency department after an intentional overdose of amitriptyline. He is drowsy, hypotensive, and his ECG shows a QRS duration of 140 ms. What is the most appropriate immediate pharmacologic treatment?

Accepted Answer

Intravenous sodium bicarbonate bolus and infusion

Answer

Intravenous magnesium sulfate

Answer

Intravenous calcium gluconate

Answer

High-dose beta-blocker therapy

Answer

Intravenous lidocaine

Practice question

A 35-year-old man presents to the emergency department after an intentional overdose of amitriptyline. He is drowsy, hypotensive, and his ECG shows a QRS duration of 140 ms. What is the most appropriate immediate pharmacologic treatment?