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MediumMusculoskeletalOsteoarthritis pain management in elderlyau-racgpau-amc

A 79-year-old woman with osteoarthritis of the knees takes regular paracetamol. She has CKD stage 3, hypertension and a previous peptic ulcer bleed. According to Australian pain and opioid stewardship guidance, what is the MOST appropriate next-line pharmacological option for her chronic knee pain?

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