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MediumPalliative CareOpioid rotationca-mccqe1ca-ccfp

A 68-year-old man with metastatic lung cancer has severe pain despite taking oral morphine 120 mg/day in divided doses. You consider rotating to oral hydromorphone. Using common Canadian equianalgesic ratios (approximately 5:1 morphine:hydromorphone for oral formulations), what is an approximate total daily oral hydromorphone dose before accounting for incomplete cross-tolerance?

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