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MediumPsychiatryMajor depressive disorderca-mccqe1ca-ccfp

A 38-year-old woman presents with a 6-week history of low mood, anhedonia, fatigue, impaired concentration and early morning wakening. She has no history of mania or psychosis and denies substance misuse. There is functional impairment at work but no active suicidal plan. According to current CANMAT guidelines, which is the most appropriate first-line management?

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