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HardCardiologyST-elevation myocardial infarctionca-mccqe1ca-rcpsc-em

A 58-year-old man presents to a rural emergency department 60 minutes after onset of severe central chest pain. ECG shows 3 mm ST elevation in leads V2-V4. The nearest percutaneous coronary intervention (PCI) centre is 250 km away, and transport time is estimated at 3 hours. A helicopter is unavailable due to weather. What is the most appropriate reperfusion strategy?

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