Question

A 52-year-old man with obesity and a sedentary lifestyle is diagnosed with type 2 diabetes after an HbA1c of 8.2% (66 mmol/mol). He has no established cardiovascular disease or chronic kidney disease. What is the recommended first-line pharmacological therapy in addition to lifestyle modification?

Accepted Answer

Start metformin as monotherapy

Answer

Start gliclazide modified-release monotherapy

Answer

Start premixed insulin twice daily

Answer

Start a sodium-glucose co-transporter 2 (SGLT2) inhibitor as monotherapy

Answer

Start a dipeptidyl peptidase-4 (DPP-4) inhibitor as monotherapy

Practice question

A 52-year-old man with obesity and a sedentary lifestyle is diagnosed with type 2 diabetes after an HbA1c of 8.2% (66 mmol/mol). He has no established cardiovascular disease or chronic kidney disease. What is the recommended first-line pharmacological therapy in addition to lifestyle modification?