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MediumRespiratoryAcute exacerbation of COPDau-amcau-racgp

A 68-year-old man with known chronic obstructive pulmonary disease (COPD) presents with an increase in breathlessness, a change in sputum to yellow-green and increased sputum volume over 3 days. He has no radiographic consolidation and remains haemodynamically stable. According to COPD-X guidelines, what is the main indication for starting antibiotics in an acute COPD exacerbation?

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