A 48-year-old woman with newly diagnosed rheumatoid arthritis has persistent joint pain and swelling in hands and feet for 4 months. Inflammatory markers are elevated. What is the most appropriate initial disease-modifying pharmacological therapy?AStart methotrexate with folic acid supplementationBStart long-term high-dose NSAIDs onlyCDelay DMARDs until radiographic erosions occurDUse corticosteroids alone as long-term monotherapyEStart hydroxychloroquine only for severe diseaseCheck my answer