Question

A 52-year-old woman with long-standing poorly controlled rheumatoid arthritis has swollen, tender MCP and PIP joints. She has never received a disease-modifying antirheumatic drug (DMARD). According to Canadian rheumatology guidance, what is the MOST appropriate initial DMARD?

Accepted Answer

Methotrexate

Answer

Hydroxychloroquine

Answer

Sulfasalazine

Answer

Azathioprine

Answer

Biologic agent (e.g., anti-TNF) as monotherapy

Practice question

A 52-year-old woman with long-standing poorly controlled rheumatoid arthritis has swollen, tender MCP and PIP joints. She has never received a disease-modifying antirheumatic drug (DMARD). According to Canadian rheumatology guidance, what is the MOST appropriate initial DMARD?