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EasyPsychiatryMajor depressive disorder - first-line pharmacotherapyca-mccqe1ca-ccfp

A 24-year-old woman presents with a 3-week history of low mood, anhedonia, early morning wakening and impaired concentration. She has no history of mania or hypomania and no significant medical comorbidities. According to CANMAT 2023 depression guidelines, what is the MOST appropriate initial pharmacologic approach, assuming she chooses medication?

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