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MediumRespiratoryCOPD exacerbationau-amcau-racp

A 69-year-old man with known COPD (FEV1 40% predicted) presents with increased dyspnoea, cough and purulent sputum for 3 days. Saturations are 90% on room air, respiratory rate 24 breaths/min, temperature 37.8 °C. There are no signs of pneumonia. What is the most appropriate initial management of this exacerbation?

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