Question

A 59-year-old man presents with a first episode of unprovoked proximal deep vein thrombosis confirmed on ultrasound. He has normal renal function and no active cancer. According to contemporary Canadian practice, what is the preferred initial anticoagulant strategy?

Accepted Answer

Direct oral anticoagulant such as apixaban or rivaroxaban.

Answer

Low-molecular-weight heparin alone for 3 months.

Answer

Warfarin with low-molecular-weight heparin bridging to an INR of 2-3.

Answer

Acetylsalicylic acid 81 mg daily alone.

Answer

No anticoagulation; use compression stockings only.

Practice question

A 59-year-old man presents with a first episode of unprovoked proximal deep vein thrombosis confirmed on ultrasound. He has normal renal function and no active cancer. According to contemporary Canadian practice, what is the preferred initial anticoagulant strategy?