Question

A 50-year-old man with chronic hepatitis C genotype 1 and compensated cirrhosis attends a rural general practice. He has no history of treatment. Highly effective direct-acting antiviral therapies are now widely available in Australia. What is the most appropriate management?

Accepted Answer

Initiate appropriate pan-genotypic direct-acting antiviral therapy under shared care or refer to a specialist experienced in HCV treatment

Answer

Advise that interferon-based therapy is required and refer to tertiary centre

Answer

Adopt a watchful waiting approach as he is asymptomatic

Answer

Commence long-term ribavirin monotherapy

Answer

No treatment is required if his ALT is normal

Practice question

A 50-year-old man with chronic hepatitis C genotype 1 and compensated cirrhosis attends a rural general practice. He has no history of treatment. Highly effective direct-acting antiviral therapies are now widely available in Australia. What is the most appropriate management?