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HardCardiologyChronic systolic heart failure optimisationau-racpau-amc

A 68-year-old man with ischaemic cardiomyopathy (LVEF 30 percent), NYHA class II symptoms, and optimal doses of perindopril and bisoprolol remains mildly symptomatic. His BP is 118/70 mmHg, K⁺ 4.5 mmol/L and eGFR 65 mL/min/1.73 m². Which medication should be added next to reduce mortality in line with guideline-directed therapy?

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