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MediumPsychiatryModerate major depressive disorder managementau-amcau-racgp

A 45-year-old woman presents to her GP with low mood, anhedonia, poor sleep and impaired concentration for 6 weeks, affecting her work. She denies suicidal ideation. Mental state examination is consistent with moderate major depressive disorder. According to Australian guidance, what is the most appropriate first-line management approach?

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