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MediumRespiratoryChronic obstructive pulmonary diseaseau-amcau-racgpau-racp

A 68-year-old man with a 40-pack-year smoking history presents with increasing shortness of breath and sputum production. Spirometry confirms COPD with FEV1 45% predicted. He has two moderate exacerbations requiring oral corticosteroids and antibiotics in the past year despite regular tiotropium. According to the Australian COPD approach, which is the most appropriate next step?

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