HardRespiratoryLife-threatening acute severe asthmaau-amcau-acem
A 19-year-old man with severe acute asthma presents with exhaustion, a silent chest, SpO₂ 88% on 15 L oxygen via non-rebreather mask, and PCO₂ rising to normal on arterial blood gas. He has had continuous nebulised salbutamol and IV hydrocortisone. What is the most appropriate next step?