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EasyPsychiatryMajor depressive disorderau-amcau-racgp

A 45-year-old woman presents with low mood, anhedonia, early morning wakening and poor concentration for 6 weeks. She has no history of mania, psychosis or substance misuse, and there is no immediate suicide risk. She is functioning at work but struggling. After assessment, you diagnose a first episode of moderate major depressive disorder. What is the most appropriate initial management plan in general practice?

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