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MediumCardiologyST-elevation myocardial infarctionau-amcau-racpau-acem

A 63-year-old man presents to the emergency department with central chest pain for 45 minutes at rest. His ECG shows 2 mm ST elevation in leads II, III and aVF. He lives in a rural town; the nearest PCI-capable centre is 3 hours away by road and no retrieval aircraft is immediately available. It is now 60 minutes since onset of pain. What is the most appropriate reperfusion strategy?

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