Question

A 69-year-old man with HFrEF and persistent symptoms asks about SGLT2 initiation. eGFR is 26. Any dose restrictions?

Accepted Answer

Initiate per labeling; SGLT2 inhibitors confer HF benefits at low eGFR with glycemic effect diminished

Answer

Cannot use below eGFR 45

Answer

Contraindicated if EF <35%

Answer

Only for diabetes, not HF

Answer

Use only with insulin

Practice question

A 69-year-old man with HFrEF and persistent symptoms asks about SGLT2 initiation. eGFR is 26. Any dose restrictions?