Question

A 72-year-old with confirmed CDI and fulminant colitis (hypotension, ileus). Best initial antimicrobial therapy?

Accepted Answer

Oral vancomycin 500 mg QID plus IV metronidazole 500 mg q8h (consider rectal vancomycin if ileus)

Answer

Fidaxomicin 200 mg BID only

Answer

Metronidazole alone

Answer

Probiotics

Answer

No antibiotics; surgery first

Practice question

A 72-year-old with confirmed CDI and fulminant colitis (hypotension, ileus). Best initial antimicrobial therapy?