Question

A 45-year-old overweight adult with diabetes (A1C 8.1%), ASCVD, and eGFR 60 asks about cardioprotective agents. Best next step in addition to metformin?

Accepted Answer

Add an SGLT2 inhibitor or GLP-1RA with proven CV benefit

Answer

Add sulfonylurea as first add-on

Answer

Add TZD regardless of weight gain

Answer

Add DPP-4 inhibitor for CV protection

Answer

Delay intensification until A1C >=9%

Practice question

A 45-year-old overweight adult with diabetes (A1C 8.1%), ASCVD, and eGFR 60 asks about cardioprotective agents. Best next step in addition to metformin?