Question

A 72-year-old with persistent AF (CHA₂DS₂-VASc 5) on warfarin with labile INRs asks about DOACs. No mechanical valve, CrCl 45 mL/min. Best recommendation?

Accepted Answer

Switch to DOAC due to lower stroke risk vs warfarin

Answer

Continue warfarin because of age

Answer

Switch to DOAC because it is indicated in mechanical valves

Answer

Switch to aspirin alone

Answer

Stop anticoagulation due to fall risk

Practice question

A 72-year-old with persistent AF (CHA₂DS₂-VASc 5) on warfarin with labile INRs asks about DOACs. No mechanical valve, CrCl 45 mL/min. Best recommendation?